Radiation protection centre (RSC) is involved in the IAEA Coordinated Research Project (CRP) E35010 titled “Applications of biological dosimetry methods in radiation oncology, nuclear medicine, diagnostic and interventional radiology” (MEDBIODOSE) that was launched in 2017 and end in early 2021.
The main aim of the project that brings together 25 institutions from 23 IAEA Member States is sustaining and enhancing the scope of biodosimetry services to medicine as well as filing in gaps in knowledge, developing new approaches to assist with the transition to personalized medicine and improving the quality of health care using radiation technologies.
This is a continuation project initiated following the successful implementation of the IAEA coordinated research project (CRP E35008) for 2014-2016 " Strengthening of Biological dosimetry”in IAEA Member States: Improvement of current techniques and intensification of collaboration and networking among the different institutes". In order to support the IAEA initiative to expand the scope of cytogenetic methods, the RSC together with Klaipėda University Hospital (hereinafter referred to as KUL) in 2014 launched first study in Lithuania on link between frequency of acute and late radiotherapy related side effects among cancer patients and their radiosensitivity estimated using cytogenetic methods. In order to continue activity in radiosensitivity research and implements the goals of the coordinated research project of the IAEA, RSC together with KUL and National Cancer Institute in 2017-2021 continue on investigation of association between individual radiosensitivity and development of radiotherapy induced adverse effects among cancer patients.
After MEDBIODOSE is completed, it is expected, that research network for clinical applications of biological dosimetry will be established to facilitate dialogue between biodosimetry specialists and radiation oncologists, collect biodosimetry data on patients exposed to radiation for medical purposes, develop biodosimetry based methods for prediction of adverse radiotherapy effects allowing refinement of radiation treatment plans, propose and test biodosimetry methodology for comprehensive assessment of consequences of medical radiation exposures, including accidental overexposure and transfer biodosimetry methodology into clinical practice in order to improve outcome of radiation medical services in terms of survival, safety and quality of life.
Last update: 28 February 2019